STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)    
Predicted Functional Partners:
M3XM02_MUSPF
Tr-type G domain-containing protein.
 
  
  0.922
SIRT1
Sirtuin 1.
    
 0.863
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.844
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
    
 0.844
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
    
  0.841
PLOD3
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3.
    
  0.841
RRP8
Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...]
   
 0.835
CDYL
Chromodomain Y like.
   
 0.760
CDYL2
Chromodomain Y like 2.
   
 0.760
DDB1
Damage specific DNA binding protein 1.
    
 
 0.695
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.