node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL6 | HDAC1 | ENSMPUP00000003385 | ENSMPUP00000015122 | BCL6 transcription repressor. | Histone deacetylase 1. | 0.640 |
BCL6 | HDAC2 | ENSMPUP00000003385 | ENSMPUP00000010193 | BCL6 transcription repressor. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.640 |
BCL6 | NCOR1 | ENSMPUP00000003385 | ENSMPUP00000010116 | BCL6 transcription repressor. | Nuclear receptor corepressor 1. | 0.939 |
BCL6 | NCOR2 | ENSMPUP00000003385 | ENSMPUP00000001405 | BCL6 transcription repressor. | Nuclear receptor corepressor 2. | 0.941 |
HDAC1 | BCL6 | ENSMPUP00000015122 | ENSMPUP00000003385 | Histone deacetylase 1. | BCL6 transcription repressor. | 0.640 |
HDAC1 | HDAC2 | ENSMPUP00000015122 | ENSMPUP00000010193 | Histone deacetylase 1. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.975 |
HDAC1 | HDAC3 | ENSMPUP00000015122 | ENSMPUP00000008127 | Histone deacetylase 1. | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.938 |
HDAC1 | NCOR1 | ENSMPUP00000015122 | ENSMPUP00000010116 | Histone deacetylase 1. | Nuclear receptor corepressor 1. | 0.965 |
HDAC1 | NCOR2 | ENSMPUP00000015122 | ENSMPUP00000001405 | Histone deacetylase 1. | Nuclear receptor corepressor 2. | 0.936 |
HDAC1 | PPARG | ENSMPUP00000015122 | ENSMPUP00000017072 | Histone deacetylase 1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.454 |
HDAC1 | RBPJ | ENSMPUP00000015122 | ENSMPUP00000016611 | Histone deacetylase 1. | Recombination signal binding protein for immunoglobulin kappa J region. | 0.952 |
HDAC1 | RBPJL | ENSMPUP00000015122 | ENSMPUP00000017524 | Histone deacetylase 1. | Recombination signal binding protein for immunoglobulin kappa J region like. | 0.940 |
HDAC2 | BCL6 | ENSMPUP00000010193 | ENSMPUP00000003385 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | BCL6 transcription repressor. | 0.640 |
HDAC2 | HDAC1 | ENSMPUP00000010193 | ENSMPUP00000015122 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Histone deacetylase 1. | 0.975 |
HDAC2 | HDAC3 | ENSMPUP00000010193 | ENSMPUP00000008127 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.938 |
HDAC2 | NCOR1 | ENSMPUP00000010193 | ENSMPUP00000010116 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 1. | 0.965 |
HDAC2 | NCOR2 | ENSMPUP00000010193 | ENSMPUP00000001405 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 2. | 0.936 |
HDAC2 | PPARG | ENSMPUP00000010193 | ENSMPUP00000017072 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.454 |
HDAC2 | RBPJ | ENSMPUP00000010193 | ENSMPUP00000016611 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Recombination signal binding protein for immunoglobulin kappa J region. | 0.953 |
HDAC2 | RBPJL | ENSMPUP00000010193 | ENSMPUP00000017524 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Recombination signal binding protein for immunoglobulin kappa J region like. | 0.940 |