STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LONRF3LON peptidase N-terminal domain and ring finger 3. (763 aa)    
Predicted Functional Partners:
RPS27A
Ubiquitin-like domain-containing protein.
   
  0.583
M3YFD0_MUSPF
Uncharacterized protein.
    
 0.568
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.549
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.548
MST1R
Macrophage stimulating 1 receptor.
    
 
 0.531
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3.
      
 0.526
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
     
 0.482
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
     
0.481
TRIP12
Thyroid hormone receptor interactor 12.
    
 0.465
ZDHHC15
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.463
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.