STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES1Hes family bHLH transcription factor 1. (283 aa)    
Predicted Functional Partners:
FANCG
FA complementation group G.
   
 0.957
FANCL
FA complementation group L.
    
 0.957
FANCA
FA complementation group A.
    
 0.957
FANCF
FA complementation group F.
    
 0.957
FANCC
Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
    
  0.956
FANCE
FA complementation group E.
    
  0.920
M3XWT8_MUSPF
Uncharacterized protein.
    
  0.917
NEUROG3
Neurogenin 3.
   
 0.915
FANCD2
FA complementation group D2.
     
 0.906
UBE2T
Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.850
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.