| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APH1A | APH1B | ENSMPUP00000005199 | ENSMPUP00000000633 | Aph-1 homolog A, gamma-secretase subunit. | Aph-1 homolog B, gamma-secretase subunit. | 0.924 |
| APH1A | APP | ENSMPUP00000005199 | ENSMPUP00000000998 | Aph-1 homolog A, gamma-secretase subunit. | Amyloid beta precursor protein. | 0.612 |
| APH1A | NCSTN | ENSMPUP00000005199 | ENSMPUP00000013999 | Aph-1 homolog A, gamma-secretase subunit. | Nicastrin. | 0.992 |
| APH1A | NOTCH1 | ENSMPUP00000005199 | ENSMPUP00000011233 | Aph-1 homolog A, gamma-secretase subunit. | Notch receptor 1. | 0.893 |
| APH1A | NOTCH4 | ENSMPUP00000005199 | ENSMPUP00000010033 | Aph-1 homolog A, gamma-secretase subunit. | Notch receptor 4. | 0.890 |
| APH1A | PSEN1 | ENSMPUP00000005199 | ENSMPUP00000003675 | Aph-1 homolog A, gamma-secretase subunit. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.991 |
| APH1A | PSEN2 | ENSMPUP00000005199 | ENSMPUP00000015742 | Aph-1 homolog A, gamma-secretase subunit. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.990 |
| APH1A | PSENEN | ENSMPUP00000005199 | ENSMPUP00000006068 | Aph-1 homolog A, gamma-secretase subunit. | Presenilin enhancer, gamma-secretase subunit. | 0.989 |
| APH1B | APH1A | ENSMPUP00000000633 | ENSMPUP00000005199 | Aph-1 homolog B, gamma-secretase subunit. | Aph-1 homolog A, gamma-secretase subunit. | 0.924 |
| APH1B | APP | ENSMPUP00000000633 | ENSMPUP00000000998 | Aph-1 homolog B, gamma-secretase subunit. | Amyloid beta precursor protein. | 0.612 |
| APH1B | NCSTN | ENSMPUP00000000633 | ENSMPUP00000013999 | Aph-1 homolog B, gamma-secretase subunit. | Nicastrin. | 0.993 |
| APH1B | NOTCH1 | ENSMPUP00000000633 | ENSMPUP00000011233 | Aph-1 homolog B, gamma-secretase subunit. | Notch receptor 1. | 0.885 |
| APH1B | NOTCH4 | ENSMPUP00000000633 | ENSMPUP00000010033 | Aph-1 homolog B, gamma-secretase subunit. | Notch receptor 4. | 0.888 |
| APH1B | PSEN1 | ENSMPUP00000000633 | ENSMPUP00000003675 | Aph-1 homolog B, gamma-secretase subunit. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.992 |
| APH1B | PSEN2 | ENSMPUP00000000633 | ENSMPUP00000015742 | Aph-1 homolog B, gamma-secretase subunit. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.992 |
| APH1B | PSENEN | ENSMPUP00000000633 | ENSMPUP00000006068 | Aph-1 homolog B, gamma-secretase subunit. | Presenilin enhancer, gamma-secretase subunit. | 0.989 |
| APP | APH1A | ENSMPUP00000000998 | ENSMPUP00000005199 | Amyloid beta precursor protein. | Aph-1 homolog A, gamma-secretase subunit. | 0.612 |
| APP | APH1B | ENSMPUP00000000998 | ENSMPUP00000000633 | Amyloid beta precursor protein. | Aph-1 homolog B, gamma-secretase subunit. | 0.612 |
| APP | CTNNB1 | ENSMPUP00000000998 | ENSMPUP00000011461 | Amyloid beta precursor protein. | Catenin beta 1. | 0.470 |
| APP | GSK3B | ENSMPUP00000000998 | ENSMPUP00000008296 | Amyloid beta precursor protein. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.706 |
