STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BDH13-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)    
Predicted Functional Partners:
BDH2
3-hydroxybutyrate dehydrogenase 2.
   
 
 0.979
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
     
 0.975
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
     
 0.974
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
     
 0.957
AACS
Acetoacetyl-CoA synthetase.
     
 0.911
ACAT1
Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.748
APEH
Acylaminoacyl-peptide hydrolase.
      
 0.696
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
      
 0.660
NOTCH2
Notch receptor 2.
      
 0.594
PHGDH
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 
 0.543
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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