STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)    
Predicted Functional Partners:
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
  
 
 0.952
MMP8
Matrix metallopeptidase 8.
   
 0.938
SLPI
Secretory leukocyte peptidase inhibitor.
    
 0.936
C5
Complement C5.
   
 0.891
MMP7
Matrix metallopeptidase 7.
   
 0.874
GZMB
Granzyme B; Belongs to the peptidase S1 family.
  
0.838
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
  
0.838
PLG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
 
 
0.797
M3XVV7_MUSPF
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.794
CD177
CD177 molecule.
   
 0.777
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.