STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX57DExH-box helicase 57. (1383 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
  0.878
ITSN1
Intersectin 1.
   
  0.759
M3XQF6_MUSPF
DH domain-containing protein.
   
  0.759
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
    
 
 0.746
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.735
M3Z164_MUSPF
Uncharacterized protein.
   
 0.671
DDX60
DExD/H-box helicase 60.
   
 0.654
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.649
MLST8
MTOR associated protein, LST8 homolog.
   
  
 0.639
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.634
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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