CUBN protein (Mustela putorius) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

CUBN

Cubilin. (3619 aa)

Predicted Functional Partners:

CBLIF

0.993

M3XU23_MUSPF

0.990

TCN1

0.974

GC

0.973

LRP2

0.812

ALB

0.755

SLC17A1

0.750

TCN2

0.692

PDZK1

0.638

M3Y8T6_MUSPF

0.619

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CUBN	ENSMPUP00000009221	ENSMPUP00000011430	Albumin.	Cubilin.	0.755
ALB	GC	ENSMPUP00000009221	ENSMPUP00000009283	Albumin.	GC vitamin D binding protein.	0.577
ALB	LRP2	ENSMPUP00000009221	ENSMPUP00000000737	Albumin.	LDL receptor related protein 2.	0.501
ALB	M3Y8T6_MUSPF	ENSMPUP00000009221	ENSMPUP00000007743	Albumin.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.841
CBLIF	CUBN	ENSMPUP00000014455	ENSMPUP00000011430	Cobalamin binding intrinsic factor.	Cubilin.	0.993
CBLIF	M3XU23_MUSPF	ENSMPUP00000014455	ENSMPUP00000002573	Cobalamin binding intrinsic factor.	Uncharacterized protein.	0.496
CBLIF	TCN1	ENSMPUP00000014455	ENSMPUP00000014451	Cobalamin binding intrinsic factor.	Transcobalamin 1.	0.933
CBLIF	TCN2	ENSMPUP00000014455	ENSMPUP00000012844	Cobalamin binding intrinsic factor.	Transcobalamin 2.	0.522
CUBN	ALB	ENSMPUP00000011430	ENSMPUP00000009221	Cubilin.	Albumin.	0.755
CUBN	CBLIF	ENSMPUP00000011430	ENSMPUP00000014455	Cubilin.	Cobalamin binding intrinsic factor.	0.993
CUBN	GC	ENSMPUP00000011430	ENSMPUP00000009283	Cubilin.	GC vitamin D binding protein.	0.973
CUBN	LRP2	ENSMPUP00000011430	ENSMPUP00000000737	Cubilin.	LDL receptor related protein 2.	0.812
CUBN	M3XU23_MUSPF	ENSMPUP00000011430	ENSMPUP00000002573	Cubilin.	Uncharacterized protein.	0.990
CUBN	M3Y8T6_MUSPF	ENSMPUP00000011430	ENSMPUP00000007743	Cubilin.	Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.	0.619
CUBN	PDZK1	ENSMPUP00000011430	ENSMPUP00000000625	Cubilin.	PDZ domain containing 1.	0.638
CUBN	SLC17A1	ENSMPUP00000011430	ENSMPUP00000008685	Cubilin.	Solute carrier family 17 member 1.	0.750
CUBN	TCN1	ENSMPUP00000011430	ENSMPUP00000014451	Cubilin.	Transcobalamin 1.	0.974
CUBN	TCN2	ENSMPUP00000011430	ENSMPUP00000012844	Cubilin.	Transcobalamin 2.	0.692
GC	ALB	ENSMPUP00000009283	ENSMPUP00000009221	GC vitamin D binding protein.	Albumin.	0.577
GC	CUBN	ENSMPUP00000009283	ENSMPUP00000011430	GC vitamin D binding protein.	Cubilin.	0.973