IL1R2 protein (Mustela putorius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IL1R2

Interleukin 1 receptor type 2. (414 aa)

Predicted Functional Partners:

IL1B

0.996

IL1A

0.985

IL1RN

0.964

IL1R1

0.960

IL1RAP

0.906

IL1RL2

0.906

IL36RN

0.688

IL6R

0.570

RGS14

0.567

IFNAR1

0.540

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNAR1	IL1B	ENSMPUP00000001254	ENSMPUP00000010696	Interferon alpha and beta receptor subunit 1.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.524
IFNAR1	IL1R2	ENSMPUP00000001254	ENSMPUP00000012138	Interferon alpha and beta receptor subunit 1.	Interleukin 1 receptor type 2.	0.540
IFNAR1	IL6R	ENSMPUP00000001254	ENSMPUP00000007289	Interferon alpha and beta receptor subunit 1.	Interleukin 6 receptor.	0.829
IL1A	IL1B	ENSMPUP00000009661	ENSMPUP00000010696	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	0.999
IL1A	IL1R1	ENSMPUP00000009661	ENSMPUP00000012143	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.979
IL1A	IL1R2	ENSMPUP00000009661	ENSMPUP00000012138	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor type 2.	0.985
IL1A	IL1RAP	ENSMPUP00000009661	ENSMPUP00000003452	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.924
IL1A	IL1RL2	ENSMPUP00000009661	ENSMPUP00000012149	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.951
IL1A	IL1RN	ENSMPUP00000009661	ENSMPUP00000009465	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.835
IL1A	IL36RN	ENSMPUP00000009661	ENSMPUP00000009495	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.716
IL1B	IFNAR1	ENSMPUP00000010696	ENSMPUP00000001254	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interferon alpha and beta receptor subunit 1.	0.524
IL1B	IL1A	ENSMPUP00000010696	ENSMPUP00000009661	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.999
IL1B	IL1R1	ENSMPUP00000010696	ENSMPUP00000012143	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.993
IL1B	IL1R2	ENSMPUP00000010696	ENSMPUP00000012138	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 1 receptor type 2.	0.996
IL1B	IL1RAP	ENSMPUP00000010696	ENSMPUP00000003452	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 1 receptor accessory protein.	0.990
IL1B	IL1RL2	ENSMPUP00000010696	ENSMPUP00000012149	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 1 receptor like 2.	0.965
IL1B	IL1RN	ENSMPUP00000010696	ENSMPUP00000009465	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.684
IL1B	IL36RN	ENSMPUP00000010696	ENSMPUP00000009495	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin-1.	0.581
IL1B	IL6R	ENSMPUP00000010696	ENSMPUP00000007289	Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family.	Interleukin 6 receptor.	0.561
IL1R1	IL1A	ENSMPUP00000012143	ENSMPUP00000009661	Interleukin 1 receptor type 1.	Interleukin-1; Belongs to the IL-1 family.	0.979