STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (477 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
   
 0.995
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
    
 0.906
LRP6
LDL receptor related protein 6.
    
 0.858
LRP5
Uncharacterized protein.
    
 0.845
CENPT
Centromere protein T.
   
 0.747
CENPW
Centromere protein W.
   
 0.742
M3Y292_MUSPF
Uncharacterized protein.
      
 0.689
ACBD4
Acyl-CoA binding domain containing 4.
      
 0.675
DKK4
Dickkopf WNT signaling pathway inhibitor 4.
    
 0.647
FAM111A
Family with sequence similarity 111 member A.
      
 0.620
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.