STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC134Coiled-coil domain containing 134. (192 aa)    
Predicted Functional Partners:
SGMS2
Sphingomyelin synthase 2.
      
 0.816
XPO1
Exportin 1.
     
 0.741
ZBTB20
Zinc finger and BTB domain containing 20.
    
 0.637
MEI1
Meiotic double-stranded break formation protein 1.
 
    
 0.618
CAV2
Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...]
   
 0.535
M3YM22_MUSPF
Ig-like domain-containing protein.
    
 0.533
ZMYND8
Zinc finger MYND-type containing 8.
    
 
 0.528
DUSP5
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 
 0.525
TMEM38B
Transmembrane protein 38B.
      
 0.519
SREBF2
Sterol regulatory element binding transcription factor 2.
 
   
 0.516
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.