MECOM protein (Mustela putorius) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

MECOM

MDS1 and EVI1 complex locus. (1212 aa)

Predicted Functional Partners:

CTBP1

0.955

HDAC2

0.943

HDAC1

0.943

MAPK9

0.935

RUNX1

0.934

M3XUB3_MUSPF

0.883

ENSMPUP00000018030

0.883

MAPK10

0.837

MAPK8

0.837

RBBP7

0.794

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP1	ENSMPUP00000018030	ENSMPUP00000011090	ENSMPUP00000018030	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	annotation not available	0.868
CTBP1	HDAC1	ENSMPUP00000011090	ENSMPUP00000015122	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1.	0.939
CTBP1	HDAC2	ENSMPUP00000011090	ENSMPUP00000010193	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.939
CTBP1	M3XUB3_MUSPF	ENSMPUP00000011090	ENSMPUP00000002663	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.870
CTBP1	MECOM	ENSMPUP00000011090	ENSMPUP00000016975	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	MDS1 and EVI1 complex locus.	0.955
CTBP1	RUNX1	ENSMPUP00000011090	ENSMPUP00000001329	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.867
ENSMPUP00000018030	CTBP1	ENSMPUP00000018030	ENSMPUP00000011090	annotation not available	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.868
ENSMPUP00000018030	HDAC1	ENSMPUP00000018030	ENSMPUP00000015122	annotation not available	Histone deacetylase 1.	0.893
ENSMPUP00000018030	HDAC2	ENSMPUP00000018030	ENSMPUP00000010193	annotation not available	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
ENSMPUP00000018030	MECOM	ENSMPUP00000018030	ENSMPUP00000016975	annotation not available	MDS1 and EVI1 complex locus.	0.883
ENSMPUP00000018030	RUNX1	ENSMPUP00000018030	ENSMPUP00000001329	annotation not available	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.850
HDAC1	CTBP1	ENSMPUP00000015122	ENSMPUP00000011090	Histone deacetylase 1.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.939
HDAC1	ENSMPUP00000018030	ENSMPUP00000015122	ENSMPUP00000018030	Histone deacetylase 1.	annotation not available	0.893
HDAC1	HDAC2	ENSMPUP00000015122	ENSMPUP00000010193	Histone deacetylase 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.975
HDAC1	M3XUB3_MUSPF	ENSMPUP00000015122	ENSMPUP00000002663	Histone deacetylase 1.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.893
HDAC1	MECOM	ENSMPUP00000015122	ENSMPUP00000016975	Histone deacetylase 1.	MDS1 and EVI1 complex locus.	0.943
HDAC1	RBBP7	ENSMPUP00000015122	ENSMPUP00000002789	Histone deacetylase 1.	RB binding protein 7, chromatin remodeling factor.	0.903
HDAC1	RUNX1	ENSMPUP00000015122	ENSMPUP00000001329	Histone deacetylase 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.946
HDAC2	CTBP1	ENSMPUP00000010193	ENSMPUP00000011090	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.939
HDAC2	ENSMPUP00000018030	ENSMPUP00000010193	ENSMPUP00000018030	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	annotation not available	0.893