node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACLY | ELOVL6 | ENSMPUP00000010572 | ENSMPUP00000008453 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | 0.653 |
ACLY | FASN | ENSMPUP00000010572 | ENSMPUP00000011079 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Fatty acid synthase. | 0.992 |
ACLY | PCK1 | ENSMPUP00000010572 | ENSMPUP00000006607 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Phosphoenolpyruvate carboxykinase 1. | 0.950 |
ACLY | THRSP | ENSMPUP00000010572 | ENSMPUP00000019701 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Thyroid hormone responsive. | 0.552 |
ELOVL6 | ACLY | ENSMPUP00000008453 | ENSMPUP00000010572 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.653 |
ELOVL6 | FASN | ENSMPUP00000008453 | ENSMPUP00000011079 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | Fatty acid synthase. | 0.874 |
ELOVL6 | GPAM | ENSMPUP00000008453 | ENSMPUP00000002028 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | 0.526 |
ELOVL6 | THRSP | ENSMPUP00000008453 | ENSMPUP00000019701 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | Thyroid hormone responsive. | 0.673 |
FASN | ACLY | ENSMPUP00000011079 | ENSMPUP00000010572 | Fatty acid synthase. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.992 |
FASN | ELOVL6 | ENSMPUP00000011079 | ENSMPUP00000008453 | Fatty acid synthase. | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | 0.874 |
FASN | GPAM | ENSMPUP00000011079 | ENSMPUP00000002028 | Fatty acid synthase. | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | 0.647 |
FASN | PCK1 | ENSMPUP00000011079 | ENSMPUP00000006607 | Fatty acid synthase. | Phosphoenolpyruvate carboxykinase 1. | 0.516 |
FASN | PLIN1 | ENSMPUP00000011079 | ENSMPUP00000015649 | Fatty acid synthase. | Perilipin; Belongs to the perilipin family. | 0.672 |
FASN | THRSP | ENSMPUP00000011079 | ENSMPUP00000019701 | Fatty acid synthase. | Thyroid hormone responsive. | 0.775 |
GPAM | ELOVL6 | ENSMPUP00000002028 | ENSMPUP00000008453 | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] | 0.526 |
GPAM | FASN | ENSMPUP00000002028 | ENSMPUP00000011079 | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | Fatty acid synthase. | 0.647 |
GPAM | THRSP | ENSMPUP00000002028 | ENSMPUP00000019701 | Glycerol-3-phosphate acyltransferase 1, mitochondrial. | Thyroid hormone responsive. | 0.531 |
MID1IP1 | THRSP | ENSMPUP00000018795 | ENSMPUP00000019701 | MID1 interacting protein 1. | Thyroid hormone responsive. | 0.927 |
MOGAT2 | THRSP | ENSMPUP00000008933 | ENSMPUP00000019701 | Monoacylglycerol O-acyltransferase 2. | Thyroid hormone responsive. | 0.532 |
PCK1 | ACLY | ENSMPUP00000006607 | ENSMPUP00000010572 | Phosphoenolpyruvate carboxykinase 1. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.950 |