STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lapBHeat shock protein YciM-like; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (391 aa)    
Predicted Functional Partners:
Tchl_2055
Putative transmembrane protein.
 
   
 0.872
Tchl_2282
Hypothetical protein.
  
     0.734
Tchl_2057
Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.703
Tchl_1947
Putative permease.
 
     0.695
ftsB
Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
     0.671
lpxH
UDP-2,3-diacylglucosamine diphosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
   
 0.651
Tchl_0851
Putative nucleotidyltransferase.
  
     0.632
Tchl_0146
Rod shape-determining protein MreD.
  
     0.624
Tchl_2053
SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
       0.586
Tchl_3278
Hypothetical protein.
 
     0.573
Your Current Organism:
Thauera chlorobenzoica
NCBI taxonomy Id: 96773
Other names: ATCC 700723, CIP 107679, DSM 18012, KCTC 12933, T. chlorobenzoica, Thauera aromatica genomovar chlorobenzoica, Thauera chlorobenzoica Song et al. 2001, strain 3CB-1
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