STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tchl_2794Cysteine desulfurase. (398 aa)    
Predicted Functional Partners:
Tchl_2795
Iron-sulfur cluster regulator IscR.
 
  
 0.994
Tchl_2792
Iron-sulfur cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.989
Tchl_1942
Molybdopterin biosynthesis protein MoeB; Belongs to the sulfur carrier protein TusA family.
   
 0.984
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 
0.975
Tchl_2211
Iron-sulfur cluster assembly scaffold protein, SufE2.
  
 0.950
Tchl_3312
Sulfur carrier protein adenylyltransferase ThiF.
   
 0.945
cyaY
Frataxin-like protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
   
 0.939
Tchl_2272
Rhodanese.
  
 0.914
Tchl_3256
Thiosulfate sulfurtransferase, rhodanese.
  
 0.914
Tchl_2791
Iron binding protein IscA for iron-sulfur cluster assembly; Belongs to the HesB/IscA family.
 
  
 0.909
Your Current Organism:
Thauera chlorobenzoica
NCBI taxonomy Id: 96773
Other names: ATCC 700723, CIP 107679, DSM 18012, KCTC 12933, T. chlorobenzoica, Thauera aromatica genomovar chlorobenzoica, Thauera chlorobenzoica Song et al. 2001, strain 3CB-1
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