STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tchl_3118Benzoylformate decarboxylase; Belongs to the TPP enzyme family. (556 aa)    
Predicted Functional Partners:
Tchl_1958
Acetolactate synthase small subunit.
 
 0.943
Tchl_0094
FMN-dependent dehydrogenase.
  
 
 0.927
Tchl_1486
Mandelate dehydrogenase.
  
 
 0.927
Tchl_1563
Putative benzaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.911
Tchl_1595
Vanillin dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.911
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.883
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.820
Tchl_3369
Acetolactate synthase small subunit.
 
 
 0.814
Tchl_3117
TRAP-type C4-dicarboxylate transport system, periplasmic component.
       0.658
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.620
Your Current Organism:
Thauera chlorobenzoica
NCBI taxonomy Id: 96773
Other names: ATCC 700723, CIP 107679, DSM 18012, KCTC 12933, T. chlorobenzoica, Thauera aromatica genomovar chlorobenzoica, Thauera chlorobenzoica Song et al. 2001, strain 3CB-1
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