MTOR protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MTOR

Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)

Predicted Functional Partners:

MLST8

0.999

AKT1S1

0.999

RPTOR

0.999

RRAGC

0.998

MAPKAP1

0.998

RICTOR

0.998

EIF4EBP1

0.997

TTI1

0.997

TELO2

0.996

DEPTOR

0.995

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1S1	DEPTOR	ENSFCAP00000030473	ENSFCAP00000010168	AKT1 substrate 1.	DEP domain containing MTOR interacting protein.	0.905
AKT1S1	EIF4EBP1	ENSFCAP00000030473	ENSFCAP00000009676	AKT1 substrate 1.	Eukaryotic translation initiation factor 4E binding protein 1.	0.951
AKT1S1	MAPKAP1	ENSFCAP00000030473	ENSFCAP00000040391	AKT1 substrate 1.	MAPK associated protein 1.	0.976
AKT1S1	MLST8	ENSFCAP00000030473	ENSFCAP00000026663	AKT1 substrate 1.	MTOR associated protein, LST8 homolog.	0.998
AKT1S1	MTOR	ENSFCAP00000030473	ENSFCAP00000000048	AKT1 substrate 1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.999
AKT1S1	RICTOR	ENSFCAP00000030473	ENSFCAP00000050255	AKT1 substrate 1.	RPTOR independent companion of MTOR complex 2.	0.632
AKT1S1	RPTOR	ENSFCAP00000030473	ENSFCAP00000041796	AKT1 substrate 1.	Regulatory associated protein of MTOR complex 1.	0.999
AKT1S1	RRAGC	ENSFCAP00000030473	ENSFCAP00000008975	AKT1 substrate 1.	Ras related GTP binding C.	0.929
AKT1S1	TELO2	ENSFCAP00000030473	ENSFCAP00000009890	AKT1 substrate 1.	Telomere maintenance 2.	0.603
AKT1S1	TTI1	ENSFCAP00000030473	ENSFCAP00000055891	AKT1 substrate 1.	TELO2 interacting protein 1.	0.632
DEPTOR	AKT1S1	ENSFCAP00000010168	ENSFCAP00000030473	DEP domain containing MTOR interacting protein.	AKT1 substrate 1.	0.905
DEPTOR	EIF4EBP1	ENSFCAP00000010168	ENSFCAP00000009676	DEP domain containing MTOR interacting protein.	Eukaryotic translation initiation factor 4E binding protein 1.	0.491
DEPTOR	MAPKAP1	ENSFCAP00000010168	ENSFCAP00000040391	DEP domain containing MTOR interacting protein.	MAPK associated protein 1.	0.959
DEPTOR	MLST8	ENSFCAP00000010168	ENSFCAP00000026663	DEP domain containing MTOR interacting protein.	MTOR associated protein, LST8 homolog.	0.999
DEPTOR	MTOR	ENSFCAP00000010168	ENSFCAP00000000048	DEP domain containing MTOR interacting protein.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.995
DEPTOR	RICTOR	ENSFCAP00000010168	ENSFCAP00000050255	DEP domain containing MTOR interacting protein.	RPTOR independent companion of MTOR complex 2.	0.984
DEPTOR	RPTOR	ENSFCAP00000010168	ENSFCAP00000041796	DEP domain containing MTOR interacting protein.	Regulatory associated protein of MTOR complex 1.	0.997
DEPTOR	RRAGC	ENSFCAP00000010168	ENSFCAP00000008975	DEP domain containing MTOR interacting protein.	Ras related GTP binding C.	0.701
DEPTOR	TELO2	ENSFCAP00000010168	ENSFCAP00000009890	DEP domain containing MTOR interacting protein.	Telomere maintenance 2.	0.450
DEPTOR	TTI1	ENSFCAP00000010168	ENSFCAP00000055891	DEP domain containing MTOR interacting protein.	TELO2 interacting protein 1.	0.920