STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANGPTL7Angiopoietin like 7. (344 aa)    
Predicted Functional Partners:
CILP
Cartilage intermediate layer protein.
   
 
 0.694
ITGBL1
Integrin subunit beta like 1.
    
 0.682
ENSFCAP00000027665
Uncharacterized protein.
 
   
 0.667
TEK
TEK receptor tyrosine kinase.
   
 0.664
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
   
 0.660
ZBED9
Zinc finger BED-type containing 9.
    
 0.648
MYOC
Myocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...]
      
 0.629
SENP1
SUMO specific peptidase 1.
      
 0.577
RSPO4
R-spondin 4.
     
 0.559
FAM180A
Family with sequence similarity 180 member A.
      
 0.483
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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