STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP1A2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (512 aa)    
Predicted Functional Partners:
UGT1A
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.973
CYP3A131
Uncharacterized protein.
  
0.964
ENSFCAP00000027010
Uncharacterized protein.
  
 0.959
EPHX1
Epoxide hydrolase 1.
   
 0.957
CYP26A1
Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 0.955
LOC101087662
UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.
   
 0.953
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
  
 
0.952
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
 0.950
CYP26B1
Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.
  
0.942
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.938
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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