STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEST2Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (507 aa)    
Predicted Functional Partners:
GLUL
Glutamine synthetase.
    
 
 0.983
DEPDC1
DEP domain containing 1.
      
 0.694
RPE65
Retinoid isomerohydrolase RPE65.
      
 0.694
RTBDN
Retbindin.
      
 0.659
SLC13A4
Solute carrier family 13 member 4.
      
 0.611
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2.
      
 0.587
RLBP1
Retinaldehyde binding protein 1.
   
  
 0.563
LRAT
Lecithin retinol acyltransferase.
      
 0.562
PELO
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
 
      0.543
ANO2
Anoctamin.
   
  
 0.542
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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