Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POU5F1POU domain protein. (360 aa)    
Predicted Functional Partners:
NANOG
Nanog homeobox.
   
 0.981
SALL4
Spalt like transcription factor 4.
   
 0.979
SOX15
SRY-box 15.
    
 0.973
LOC101084379
Homeobox domain-containing protein.
   
 0.927
ENSFCAP00000037965
Homeobox domain-containing protein.
   
 0.927
CTNNB1
Catenin beta 1.
    
 0.900
SALL1
Spalt like transcription factor 1.
   
 0.887
LIN28A
Lin-28 homolog A.
   
 0.884
SOX17
SRY-box transcription factor 17.
    
 0.877
KDM1A
Lysine demethylase 1A.
    
 
 0.873
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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