STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)    
Predicted Functional Partners:
KCNQ1
Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...]
   
 
0.944
KCNE3
Potassium voltage-gated channel subfamily E regulatory subunit 3.
     
 0.943
KCNU1
Potassium calcium-activated channel subfamily U member 1.
     
 0.930
KCNMB4
Potassium calcium-activated channel subfamily M regulatory beta subunit 4.
     
 0.924
KCNN1
Potassium calcium-activated channel subfamily N member 1.
  
  
0.923
KCNJ13
Potassium voltage-gated channel subfamily J member 13.
   
 
 0.917
KCNN3
Potassium calcium-activated channel subfamily N member 3.
  
  
0.917
KCNN2
Potassium calcium-activated channel subfamily N member 2.
  
  
0.917
KCNK5
Potassium two pore domain channel subfamily K member 5.
     
 0.914
PRKCG
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 
 0.913
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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