STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD3Protein-histidine N-methyltransferase. (601 aa)    
Predicted Functional Partners:
NSD3
Nuclear receptor binding SET domain protein 3.
    
 0.714
SMYD2
SET domain-containing protein.
   
 
 0.656
KMT2C
Lysine methyltransferase 2C.
     
 0.655
KMT2D
Lysine methyltransferase 2D.
     
 0.655
ZNF142
Uncharacterized protein.
    
 0.627
CPE
Carboxypeptidase E.
      
 0.605
NSD2
Nuclear receptor binding SET domain protein 2.
    
 0.603
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
   
 
 0.593
SETD4
SET domain containing 4.
      
0.580
CAPRIN2
Caprin family member 2.
      
 0.579
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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