Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HINFPHistone H4 transcription factor. (500 aa)    
Predicted Functional Partners:
NPAT
Nuclear protein, coactivator of histone transcription.
    
 
 0.862
GSC
Goosecoid homeobox.
    
   0.804
SDK2
Sidekick cell adhesion molecule 2.
      
 0.768
ZNF318
Zinc finger protein 318.
      
 0.658
SDK1
Sidekick cell adhesion molecule 1.
      
 0.606
E2F7
E2F transcription factor 7.
      
 0.598
HMX3
H6 family homeobox 3.
    
   0.593
DCTN2
Dynactin subunit 2.
      
 0.584
LETM1
Leucine zipper and EF-hand containing transmembrane protein 1.
      
 0.554
POU2F1
POU domain protein.
      
 0.540
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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