Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC153Coiled-coil domain containing 153. (282 aa)    
Predicted Functional Partners:
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.571
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.567
KDM6A
Lysine demethylase 6A.
   
 0.495
KDM6B
Lysine demethylase 6B.
   
 0.495
EP300
E1A binding protein p300.
   
 0.449
CREBBP
CREB binding protein.
   
 0.449
CENPP
Uncharacterized protein.
   
 0.449
EED
Embryonic ectoderm development.
   
 0.427
HCFC1
Host cell factor C1.
   
 0.412
HCFC2
Host cell factor C2.
   
 0.412
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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