Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGALSLGalectin. (392 aa)    
Predicted Functional Partners:
CASTOR2
Uncharacterized protein.
      
 0.735
CDH24
Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins.
     
 0.692
LINGO2
Leucine rich repeat and Ig domain containing 2.
   
  
 0.670
UBASH3B
Ubiquitin associated and SH3 domain containing B.
      
 0.659
MRS2
Magnesium transporter.
      
 0.636
ITGB1BP1
Integrin subunit beta 1 binding protein 1.
      
 0.634
PDLIM5
PDZ and LIM domain 5.
      
 0.621
TBC1D31
TBC1 domain family member 31.
      
 0.600
ACTR3B
Uncharacterized protein; Belongs to the actin family.
      
 0.589
TFB2M
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
      
 0.582
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: medium (42%) [HD]