Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTBP1Polypyrimidine tract binding protein 1. (625 aa)    
Predicted Functional Partners:
HNRNPL
Heterogeneous nuclear ribonucleoprotein L.
   
 0.921
HNRNPK
Heterogeneous nuclear ribonucleoprotein K.
   
 0.920
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
   
 0.877
HNRNPC
RRM domain-containing protein.
   
 0.861
ELAVL1
ELAV-like protein; Belongs to the RRM elav family.
   
 0.811
RAVER1
Uncharacterized protein.
   
 0.810
QKI
Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
   
 
 0.782
HNRNPLL
Heterogeneous nuclear ribonucleoprotein L like.
   
 0.779
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
   
 0.777
HNRNPD
Heterogeneous nuclear ribonucleoprotein D.
   
 0.777
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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