Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PRSS58Serine protease 58; Belongs to the peptidase S1 family. (241 aa)    
Predicted Functional Partners:
EPHB6
EPH receptor B6.
    
 0.787
DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]
    
 
 0.702
STARD3NL
STARD3 N-terminal like.
      
 0.660
SPINK1
Serine peptidase inhibitor, Kazal type 1.
   
 0.633
TRG
Ig-like domain-containing protein.
    
 0.632
DBH
Dopamine beta-hydroxylase.
      
 0.583
TRAV3
T cell receptor alpha variable 3 (gene/pseudogene).
     
 0.583
CDR2
Cerebellar degeneration related protein 2.
      
 0.573
C17orf98
Chromosome 17 open reading frame 98.
    
 
 0.566
LOC101099923
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
  
 0.539
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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