STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)    
Predicted Functional Partners:
ERMARD
ER membrane associated RNA degradation.
     
 0.802
DCHS2
Dachsous cadherin-related 2.
   
  
 0.723
FLNA
Filamin A.
   
 
 0.715
ENSFCAP00000033958
Uncharacterized protein.
    
 0.656
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.656
ASPM
Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).
      
 0.645
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
   
 
 0.643
UBA5
Ubiquitin like modifier activating enzyme 5.
   
  
 0.639
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
  
  
0.568
RASA3
RAS p21 protein activator 3.
      
 0.527
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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