Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COL14A1Collagen type XIV alpha 1 chain. (1797 aa)    
Predicted Functional Partners:
COL4A6
Collagen type IV alpha 6 chain.
   
 0.733
COL8A2
Collagen type VIII alpha 2 chain.
  
 
0.731
COL4A2
Collagen type IV alpha 2 chain.
   
 0.720
COL1A2
Collagen type I alpha 2 chain.
   
 0.690
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
   
 0.682
SERPINH1
Serpin family H member 1; Belongs to the serpin family.
   
 0.636
COL6A2
Collagen type VI alpha 2 chain.
  
0.607
ITGB1
Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...]
   
 0.583
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
    
 0.582
LAMA2
Laminin subunit alpha 2.
   
 0.582
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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