STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (396 aa)    
Predicted Functional Partners:
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 0.948
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
   
 0.940
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.937
SACM1L
SAC1 like phosphatidylinositide phosphatase.
    
 0.926
PI4K2B
Phosphatidylinositol 4-kinase type 2 beta.
     
 0.924
PI4K2A
PI3K/PI4K domain-containing protein.
     
 0.924
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
     
 0.919
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.919
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
   
0.917
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.914
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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