Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TEAD2TEA domain transcription factor 2. (451 aa)    
Predicted Functional Partners:
YAP1
Yes associated protein 1.
   
 0.971
WWTR1
WW domain containing transcription regulator 1.
   
 0.959
TCF7
Transcription factor 7.
    
 0.906
LEF1
Lymphoid enhancer binding factor 1.
    
 0.892
TCF7L2
Transcription factor 7 like 2.
    
 0.880
TCF7L1
Transcription factor 7 like 1.
    
 0.874
WEE2
Wee1-like protein kinase.
   
  
 0.763
VGLL4
Vestigial like family member 4.
    
 
 0.750
TEAD4
TEA domain transcription factor 4.
     
  0.688
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
     
  0.680
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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