STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM2Isthmin 2. (537 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
 
 
 0.886
SORD
Sorbitol dehydrogenase.
  
 
 0.696
KDSR
3-ketodihydrosphingosine reductase.
     
 0.696
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 0.592
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.556
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.538
ADHFE1
Fe-ADH domain-containing protein.
    
 0.521
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.503
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.503
ENSFCAP00000044359
Uncharacterized protein.
    
 
 0.503
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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