Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRIT2Leucine rich repeat, Ig-like and transmembrane domains 2. (550 aa)    
Predicted Functional Partners:
LRIT1
Leucine rich repeat, Ig-like and transmembrane domains 1.
   
 0.754
CCDC126
Coiled-coil domain containing 126.
      
 0.692
SAPCD1
Suppressor APC domain containing 1.
      
 0.668
FAM169A
Family with sequence similarity 169 member A.
    
 0.628
MANSC4
MANSC domain containing 4.
    
 
 0.577
DDX28
DEAD-box helicase 28.
    
 0.574
SERPINE3
Serpin family E member 3; Belongs to the serpin family.
     
 0.547
TTC38
Tetratricopeptide repeat domain 38.
      
 0.539
FAM169B
Uncharacterized protein.
    
 0.519
KCNJ14
Potassium voltage-gated channel subfamily J member 14.
     
 0.512
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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