Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF15Rho guanine nucleotide exchange factor 15. (843 aa)    
Predicted Functional Partners:
ECT2L
Epithelial cell transforming 2 like.
     
 0.782
RHOA
Ras homolog family member A.
    
 0.704
FGD5
FYVE, RhoGEF and PH domain containing 5.
   
 
 0.668
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9.
     
 0.631
CEP55
Centrosomal protein 55.
    
   0.555
SH2D3C
SH2 domain containing 3C.
      
 0.548
CCDC42
Coiled-coil domain containing 42.
      
 0.545
EPHA8
EPH receptor A8.
    
  0.541
EPHB6
EPH receptor B6.
    
  0.540
CDC42
Uncharacterized protein.
    
 0.539
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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