Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTNNA1Catenin alpha 1. (927 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
   
 0.940
AFDN
Afadin, adherens junction formation factor.
   
 0.936
VCL
Vinculin.
   
 0.919
ACTN4
Actinin alpha 4.
   
 0.882
CDH1
Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.
   
 0.881
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
   
 0.872
CTNNA3
Catenin alpha 3.
     
 0.859
ACTN1
Actinin alpha 1.
   
 0.858
CTNND1
Catenin delta 1.
   
 0.812
YWHAH
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta.
     
 0.808
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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