TBX10 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TBX10

T-box transcription factor 10. (380 aa)

Predicted Functional Partners:

OSR2

0.489

EPC2

0.429

TBXT

0.418

TBX19

0.418

IFNG

0.414

FOXH1

0.409

TRPS1

0.409

FOXA2

0.403

FOXA1

0.403

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPC2	TBX10	ENSFCAP00000038026	ENSFCAP00000001629	Enhancer of polycomb homolog.	T-box transcription factor 10.	0.429
FOXA1	FOXA2	ENSFCAP00000020793	ENSFCAP00000011475	Forkhead box A1.	Forkhead box A2.	0.441
FOXA1	TBX10	ENSFCAP00000020793	ENSFCAP00000001629	Forkhead box A1.	T-box transcription factor 10.	0.403
FOXA1	TBX19	ENSFCAP00000020793	ENSFCAP00000013957	Forkhead box A1.	T-box transcription factor 19.	0.567
FOXA1	TBXT	ENSFCAP00000020793	ENSFCAP00000000720	Forkhead box A1.	T-box transcription factor T.	0.567
FOXA1	TRPS1	ENSFCAP00000020793	ENSFCAP00000033101	Forkhead box A1.	Transcriptional repressor GATA binding 1.	0.436
FOXA2	FOXA1	ENSFCAP00000011475	ENSFCAP00000020793	Forkhead box A2.	Forkhead box A1.	0.441
FOXA2	TBX10	ENSFCAP00000011475	ENSFCAP00000001629	Forkhead box A2.	T-box transcription factor 10.	0.403
FOXA2	TBX19	ENSFCAP00000011475	ENSFCAP00000013957	Forkhead box A2.	T-box transcription factor 19.	0.749
FOXA2	TBXT	ENSFCAP00000011475	ENSFCAP00000000720	Forkhead box A2.	T-box transcription factor T.	0.858
FOXA2	TRPS1	ENSFCAP00000011475	ENSFCAP00000033101	Forkhead box A2.	Transcriptional repressor GATA binding 1.	0.436
FOXH1	TBX10	ENSFCAP00000020406	ENSFCAP00000001629	Forkhead box H1.	T-box transcription factor 10.	0.409
FOXH1	TBX19	ENSFCAP00000020406	ENSFCAP00000013957	Forkhead box H1.	T-box transcription factor 19.	0.512
FOXH1	TBXT	ENSFCAP00000020406	ENSFCAP00000000720	Forkhead box H1.	T-box transcription factor T.	0.512
IFNG	TBX10	ENSFCAP00000008355	ENSFCAP00000001629	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	T-box transcription factor 10.	0.414
IFNG	TBX19	ENSFCAP00000008355	ENSFCAP00000013957	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	T-box transcription factor 19.	0.533
IFNG	TBXT	ENSFCAP00000008355	ENSFCAP00000000720	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.	T-box transcription factor T.	0.533
OSR2	TBX10	ENSFCAP00000041794	ENSFCAP00000001629	Odd-skipped related transciption factor 2.	T-box transcription factor 10.	0.489
TBX10	EPC2	ENSFCAP00000001629	ENSFCAP00000038026	T-box transcription factor 10.	Enhancer of polycomb homolog.	0.429
TBX10	FOXA1	ENSFCAP00000001629	ENSFCAP00000020793	T-box transcription factor 10.	Forkhead box A1.	0.403