Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101087880Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa)    
Predicted Functional Partners:
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.884
CTSK
Cathepsin S; Belongs to the peptidase C1 family.
   
  0.878
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
  
0.875
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.804
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
     
 0.788
CTSO
Cathepsin O; Belongs to the peptidase C1 family.
  
0.780
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.774
BCL2
BCL2 apoptosis regulator.
     
 0.743
BIRC3
Baculoviral IAP repeat containing 3.
   
 
 0.742
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
  0.737
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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