Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HBS1LHBS1 like translational GTPase. (686 aa)    
Predicted Functional Partners:
EXOSC7
Exosome component 7.
    
 0.987
PELO
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
   
 0.983
EXOSC8
Exosome component 8.
    
 0.981
EXOSC3
Exosome component 3.
    
 0.978
EXOSC5
Exosome component 5.
    
 0.978
EXOSC1
Exosome component 1.
    
 0.974
DIS3L
DIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.
   
 0.973
EXOSC4
Exosome component 4.
    
 0.968
EXOSC2
Exosome component 2.
    
 0.945
WDR61
WD repeat domain 61.
    
 0.937
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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