STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM43Transmembrane protein 43. (400 aa)    
Predicted Functional Partners:
ENDOD1
Endonuclease domain containing 1.
    
 0.854
NCLN
Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.
      
 0.800
TMEM33
Transmembrane protein 33.
      
 0.784
EMD
Emerin.
    
 
 0.774
SMPD4
Sphingomyelin phosphodiesterase 4.
      
 0.774
PKP2
Plakophilin 2.
      
 0.758
DSC2
Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.743
STT3B
STT3 oligosaccharyltransferase complex catalytic subunit B.
      
 0.740
JUP
Uncharacterized protein.
      
 0.735
DSG2
Desmoglein 2.
      
 0.734
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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