Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
XPCXPC complex subunit, DNA damage recognition and repair factor. (944 aa)    
Predicted Functional Partners:
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 0.992
GTF2H1
General transcription factor IIH subunit 1.
   
 0.988
DDB2
Damage specific DNA binding protein 2.
   
 0.986
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 0.977
CETN2
Centrin 2.
    
 0.971
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.970
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.969
XPA
XPA, DNA damage recognition and repair factor.
    
 0.967
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.960
GTF2H4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.949
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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