Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXO43F-box protein 43. (700 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.983
CDC20
Cell division cycle 20.
   
 0.944
CDC20B
Cell division cycle 20B.
   
 0.944
CDC27
Cell division cycle 27.
    
 0.930
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.925
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.924
FBXW11
F-box and WD repeat domain containing 11.
    
 0.912
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
   
  0.899
PPP2R1B
Protein phosphatase 2 scaffold subunit Abeta.
   
  0.899
CAMK2G
Calcium/calmodulin dependent protein kinase II gamma.
    
  0.897
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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