Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)    
Predicted Functional Partners:
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.972
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
 0.967
FOXO3
Forkhead box O3.
    
 0.948
FOXO4
Forkhead box O4.
    
 0.948
FOXO1
Forkhead box O1.
    
 0.948
FOXO6
Forkhead box O6.
    
 0.948
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.910
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
 
  
 
 0.910
SGK1
Non-specific serine/threonine protein kinase.
     
  0.894
NEDD4
NEDD4 E3 ubiquitin protein ligase.
   
 0.843
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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