Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (475 aa)    
Predicted Functional Partners:
CHRNA3
Cholinergic receptor nicotinic alpha 3 subunit.
   
 0.920
CHRNA4
Cholinergic receptor nicotinic alpha 4 subunit.
   
 0.916
LYPD6
LY6/PLAUR domain containing 6.
    
 0.911
LYPD6B
LY6/PLAUR domain containing 6B.
    
 0.909
SLURP1
Secreted LY6/PLAUR domain containing 1.
     
 0.900
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
   
 0.877
PATE2
Prostate and testis expressed 2.
     
  0.862
PATE3
Prostate and testis expressed 3.
     
  0.862
CHRNB4
Cholinergic receptor nicotinic beta 4 subunit.
   
 0.843
CHRNB2
Cholinergic receptor nicotinic beta 2 subunit.
   
 0.843
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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