STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL23RInterleukin 23 receptor. (631 aa)    
Predicted Functional Partners:
IL23A
Interleukin 23 subunit alpha.
   
 0.995
IL12RB1
Interleukin 12 receptor subunit beta 1.
   
 0.994
JAK2
Tyrosine-protein kinase.
   
 
 0.990
STAT3
Signal transducer and activator of transcription.
   
 
 0.978
IL22
Interleukin 22.
     
 0.939
TYK2
Tyrosine-protein kinase.
   
 
 0.937
CCR6
C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.
      
 0.901
JAK3
Tyrosine-protein kinase.
   
 
 0.878
RORC
RAR related orphan receptor C.
    
 
 0.861
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
 
 0.857
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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