STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND4CDENN domain containing 4C. (1957 aa)    
Predicted Functional Partners:
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
     
 0.797
MINDY1
MINDY lysine 48 deubiquitinase 1.
      
 0.765
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules.
      
 0.749
DENND5A
DENN domain containing 5A.
    
0.741
RAB10
RAB10, member RAS oncogene family.
    
 0.714
RAB8B
RAB8B, member RAS oncogene family.
    
 0.667
AVL9
AVL9 cell migration associated.
      
 0.664
DENND1A
DENN domain containing 1A.
   
 
0.641
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.620
VMP1
Vacuole membrane protein 1.
      
 0.619
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.