Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC29A4Solute carrier family 29 member 4. (633 aa)    
Predicted Functional Partners:
SLC18A2
Solute carrier family 18 member A2.
    
 
 0.694
TNRC18
Trinucleotide repeat containing 18.
      
 0.572
SMN
Survival of motor neuron protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the [...]
      
 0.541
MFSD9
Major facilitator superfamily domain containing 9.
      
 0.519
NACAD
NAC-A/B domain-containing protein.
      
 0.494
SLC22A3
Solute carrier family 22 member 3.
    
 
 0.486
NFKBIZ
NFKB inhibitor zeta.
    
 
 0.485
DYDC2
DPY30 domain containing 2.
    
 
 0.469
SLC46A2
Solute carrier family 46 member 2.
      
 0.469
TTC25
Tetratricopeptide repeat domain 25.
      
 0.456
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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