STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.729
SP6
Sp6 transcription factor.
    
 0.679
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
  
 0.555
KRTAP11-1
Keratin associated protein 11-1.
   
  
 0.523
ASB7
Ankyrin repeat and SOCS box containing 7.
    
 0.501
KRTAP3-1
Keratin associated protein 3-1.
   
 
 0.495
RANBP2
RAN binding protein 2.
   
 0.468
HSD17B14
Hydroxysteroid 17-beta dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.460
KRT82
Keratin 82; Belongs to the intermediate filament family.
  
0.459
CERT1
Ceramide transporter 1.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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