Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NCK2Cytoplasmic protein. (380 aa)    
Predicted Functional Partners:
NCK1
Cytoplasmic protein.
   
  0.992
PAK2
Non-specific serine/threonine protein kinase.
    
 0.983
EFNB2
Ephrin B2; Belongs to the ephrin family.
    
 0.982
PAK1
Non-specific serine/threonine protein kinase.
    
 0.970
PAK3
P21 (RAC1) activated kinase 3.
    
 0.970
EFNB1
Ephrin B1.
    
 0.969
LCP2
Lymphocyte cytosolic protein 2.
    
 0.968
WIPF1
WAS/WASL interacting protein family member 1.
    
 0.962
EFNB3
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
    
 0.960
WIPF2
WAS/WASL interacting protein family member 2.
    
 0.958
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.